Primary Sjögren’s Syndrome and Viruses

The etiopathogenesis of primary Sjogren’s syndrome (SS) is probably a sequential, multistep process that leads to selective damage of the exocrine glands and consequent target organ dysfunction. Although understanding of the precise mechanisms involved in etiopathogenesis of SS remains incomplete, the autoimmune origin of the disease (autoimmune epithelitis) [1] is the hypothesis postulated most commonly.