Use of arginine–glycine–aspartic acid adhesion peptides coupled with a new collagen scaffold to engineer a myocardium-like tissue graft

Cardiac tissue engineering could be useful for replacement and/or repair of diseased or malformed cardiac tissue. The creation of functional, biocompatible contractile tissues, however, remains challenging. These investigators report a novel method of engineering a highly effective collagen-cell scaffold based on arginine–glycine–aspartic acid–serine peptides cross-linked to a clinically approved collagen matrix.