Interventional revascularization for cardiovascular disease in patients with chronic kidney disease

: Chronic kidney disease (CKD) is an independent risk factor for cardiac mortality. Accelerated atherosclerosis is frequently seen in patients with CKD. However, even in drug eluting stent era, higher restenosis rate after percutaneous coronary intervention (PCI) for coronary artery disease remains a clinical limitation in patients with CKD. Similar tendency is also seen when treated with endovascular therapy (EVT) for peripheral artery disease. Thus, management for atherosclerotic disease is very difficult in patients with CKD. Recent reports have shown that improvement of devices and/or intensive medical treatment may contribute better clinical outcomes after PCI or EVT in patients with CKD. In addition, inflammatory markers such as C-reactive protein may predict worse clinical outcomes including restenosis in such population.