Synthesis and biological evaluation of novel piperidin-4-ol derivatives
2012
A series of novel piperidin-4-ol derivatives were designed, synthesized, and evaluated for potential treatment of HIV. The compounds were obtained via an efficient synthetic route in excellent yields and have been characterized by 1 H NMR, 13 C NMR, MS, and elemental analysis. The CCR5 antagonistic activities of the com- pounds have also been evaluated.
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