A high-throughput screening identifies histone deacetylase inhibitors as therapeutic agents against medulloblastoma
2019
Background
Medulloblastoma is the most frequently occurring malignant brain tumor in children. Current treatment strategies for medulloblastoma include aggressive surgery, cranio-spinal irradiation and adjuvant chemotherapy. Because current treatments can cause severe long-term side effects and are not curative, successful treatment remains a challenge.
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