Polyethylene Glycol (PEG) as a Reusable Solvent Medium for an Asymmetric Organocatalytic Michael Addition. Application to the Synthesis of Bioactive Compounds.

Karla S. Feu,Alexander F. de la Torre,Sandrina Silva,Marco A. F. de Moraes Junior,Arlene G. Corrêa,Márcio W. Paixão

Polyethylene Glycol (PEG) as a Reusable Solvent Medium for an Asymmetric Organocatalytic Michael Addition. Application to the Synthesis of Bioactive Compounds.

2014

Karla S. Feu
Alexander F. de la Torre
Sandrina Silva
Marco A. F. de Moraes Junior
Arlene G. Corrêa
Márcio W. Paixão

A highly stereoselective organocatalytic Michael addition of aldehydes to trans-β-styrenes (I) using polyethylene glycol as a recyclable solvent medium is reported.

Keywords:

Addition reaction
Polyethylene glycol
Solvent
Organocatalysis
PEG ratio
Michael reaction
Stereoselectivity
Organic chemistry
Chemistry

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