Synthesis and structure-activity relationships of 1-aminophthalazinium salts as GABAA receptor antagonists
1994
Abstract The synthesis and in vitro GABA A activity as GABA A antagonists of some 1-aminophthalazinium salts and imidazophthalazines are reported. Structure—activity relationships and a molecular modelling study allowed us to define the features which determine receptor affinity within this class of compounds.
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