Bone Metastases from Prostate Cancer: From Symptom Control to Pain Palliation

Prostate cancer is the second most frequently diagnosed cancer and the fifth leading cause of cancer-related death in men. The majority, around 90 %, of patients with metastatic castration-resistant prostate cancer (mCRPC) have radiological evidence of bone metastases, and bone is the first metastatic site in 80 % of patients [1, 2].