Abstract WMP32: Osteoprotegerin Attenuates the Growth of Intracranial Aneurysms Activating Collagen Biosynthesis and Vascular Smooth Muscle Cell Proliferation via Transforming Growth Factor-Beta1 Signaling

Takeshi Miyata,Manabu Minami,Hiroharu Kataoka,Kosuke Hayashi,Masayuki Yokode,Susumu Miyamoto

Abstract WMP32: Osteoprotegerin Attenuates the Growth of Intracranial Aneurysms Activating Collagen Biosynthesis and Vascular Smooth Muscle Cell Proliferation via Transforming Growth Factor-Beta1 Signaling

2020

Takeshi Miyata
Manabu Minami
Hiroharu Kataoka
Kosuke Hayashi
Masayuki Yokode
Susumu Miyamoto

Introduction: The pathogenesis of intracranial aneurysms (IAs) are characterized by reduced extracellular matrix and decreased number of vascular smooth muscle cells (VSMCs) in cerebral vascular wa...

Keywords:

Vascular smooth muscle
Cell growth
Cancer research
Osteoprotegerin
Cell signaling
Extracellular matrix
Diabetes mellitus
Transforming growth factor
Physical therapy
Pathogenesis
Medicine

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