Effects of Calmodulin Antisense Oligonucleotides on Chemoresponse in Paramecium

The calcium/calmodulin-regulated Ca-ATPase of the plasma membrane is implicated in Paramecium chemosensory transduction. Calmodulin antisense oligonucleotides electroporated into Paramecium disrupt chemosensory responses to sodium acetate but not to ammonium chloride.