Cu2+/Zeolite catalyzed aldol condensation: Greener synthesis of 4′-piperidinophenyl enones

Abstract A series containing twelve substituted 4′-piperidinophenyl chalcones were synthesized from crossed-aldol condensation between 4-piperidionphenyl methyl ketone and substituted benzaldehydes using solid Cu2+/Zeolite catalyzed microwave assisted method. This condensation gave more than 85% yield. The structures of chalcones were analyzed by physico-chemical properties and spectroscopic data. The influence of the catalyst was investigated by observed quantity of yields.