OP05.06: External validation of a simple ultrasound based scoring system to predict pregnancy viability beyond the first trimester

2012 
(22/41) women were discharged after the initial visit. No women in this group required repeat TVS, one woman required a repeat hCG for worsening pelvic pain. PUL outcome (i.e. failed PUL) was confirmed on Day 2 for all women; (2) 9.76% (4/41) women required repeat serum hCG levels and 50% (2/4) required repeat TVS. 75% (3/4) had a failed PUL, one woman had a persistent PUL requiring methotrexate. PUL outcome was confirmed between Days 6–16; (3) 36.6% (15/41) with hCG ratio ≥1. Repeat TVS confirmed 66.7% (10/15) women with intrauterine pregnancy, 33.3% (5/15) with ectopic pregnancy. PUL outcome was established between Days 2–16. Including all women in this study, PUL outcome was established for 56.1% (23/41) at Day 2, 12.2% (5/41) between Days 3–6, 22% (9/41) at Day 7–14, and 9.76% (4/41) at >Day 14. Conclusions: A new protocol based on predetermined hCG ratio cut-offs for women with a PUL enables a safe, consistent approach that may also have the potential to minimize the need for repeat bloods and scans in women with a PUL.
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