PHD-2 Suppression in Mesenchymal Stromal Cells Enhances Wound Healing

Sae Hee Ko,Allison Nauta,Shane D. Morrison,Michael S. Hu,Andrew Zimmermann,Michael T. Chung,Jason P. Glotzbach,Victor W. Wong,Graham G. Walmsley,H. Peter Lorenz,Denise A. Chan,Geoffrey C. Gurtner,Amato J. Giaccia,Michael T. Longaker

PHD-2 Suppression in Mesenchymal Stromal Cells Enhances Wound Healing

2018

Sae Hee Ko
Allison Nauta
Shane D. Morrison
Michael S. Hu
Andrew Zimmermann
Michael T. Chung
Jason P. Glotzbach
Victor W. Wong
Graham G. Walmsley
H. Peter Lorenz
Denise A. Chan
Geoffrey C. Gurtner
Amato J. Giaccia
Michael T. Longaker

Background:Cell therapy with mesenchymal stromal cells is a promising strategy for tissue repair. Restoration of blood flow to ischemic tissues is a key step in wound repair, and mesenchymal stromal cells have been shown to be proangiogenic. Angiogenesis is critically regulated by the hypoxia-induci

Keywords:

Anatomy
General surgery
Wound healing
Mesenchymal stem cell
Medicine
Bone marrow
tube formation
Cancer research
Surgery
Human umbilical vein endothelial cell
Angiogenesis
Umbilical vein
Cell therapy

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