Модель макулярной дегенерации сетчатки

2012 
Macular degeneration of the retina is a chronic degenerative process c primary lesion of the retinal pigment epithelium. The severity of the disease is caused by central localization process, the bilateral nature of the lesion and the slow progressive course. The experimental model of retinal epithelial povrezhdeniyapigmentnogo differing complexity of implementation, low efficiency. The aim of this work the creation of a new experimental model of macular degeneration of the retina to iucheniya pathological process. Techniques. An experiment on animals (rabbits breed Shinshu 38 eyes). On the basis of damage to the retinal pigment epithelium is created and evaluated a model of macular degeneration, defined histologically foveolyarnoy zone. Conclusion. A new experimental model determines the stability of the pathological process throughout the study, which determines the possibility of further diagnostic and therapeutic interventions in experimental conditions.
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