Study on the Relationship of Hemorheology、Blood Viscosity Syndrome、D-D and Chronic Renal Failure with Blood Stasis of TCM

Objective:To explore the relationship between Hemorheology?Blood Viscosity syndrome, Blood Stasis Syndrome(BSS) and tradition Chinese medicine(TCM)in Chronic Renal Failure(CRF).Methods:One hundred and twenty-one patients of CRF were divided into two groups by Syndrome differentiation of TCM, the Blood-Stasis-Syndrome(BSS)group(89 cases)(included 11 cases of serious BSS,35 cases of moderate BSS, and 43 cases of mild BSS),and non-Blood-Stasis-Syndrome(non-BSS)group(32 cases),and 40 cases healthy persons were enrolled as normal controlgroup. Hemorheology?Blood Stasis Syndrome analysis were measured.Results:The difference in all criteria of Hemorheology between CRF group and healthy control group was significant( P 0.05～0.01).Whole blood high shear viscosity?hematocrit(HCT)were lower significantly( P 0.05)than those in the healthy control group. Whole blood low shera viscosity?plasma viscosity(PV)?RBC aggregation (RCA) and the hypercoagulability criteria including fibrinogen(Fib)?EDW?EL were higher significantly( P 0.01)than those in the healthy control group. The hemorheology criteria including RA and hypercoagulability criteria between BSS group and non-BSS group were significant (P0.05～0.01).Blood Viscosity Syndrome(BVS)in CRF patients presented Blood High Viscosity Syndrome(BHS)?Blood High-Low Viscosity Syndrome(BHLS)?Blood Low-High Viscosity Syndrome(BLHS).The Scores of BVS were heighten gradually following Kidney function run down( P 0.01).BVS in BSS were higher significantly( P 0.01) than those in non-BSS group. The scores of BVS were heighten gradually following BSS aggravated( P 0.01). The occur rate of BSS(%) was heighten. Gradually following kidney function run down( P 0.05),the scores of BVS were heighten gradually( P 0.01).The classification of CRF patients with Blood Stasis Syndrome and the classification of Blood Viscosity Syndrome wass positive correlation( r =0.92, P 0.01).Conclusion:CRF patients with Blood Stasis presented hypercoagulabity?hypercoagulability?prethrombotic state and fibrinolytic succeeded. In the CRF patients with Blood Stasis, BVS presented BHS?BHLS.