Identification of CCR8 as a specific marker of tumor tissue-infiltrating regulatory T cells and its possibility as a therapeutic target in renal cell carcinoma

Atsunari Kawashima,Mitsunobu Matsumoto,Yujiro Kidani,Takahiro Yoshida,Makoto Matsushita,Yoko Koh,Kosuke Nakano,Yujiro Hayashi,Yu Ishizuya,Cong Wang,Taigo Kato,Takeshi Ujike,Kazutoshi Fujita,M. Uemura,Shimon Sakaguchi,M. Nagira,N. Ohkura,Hisashi Wada,Norio Nonomura

Identification of CCR8 as a specific marker of tumor tissue-infiltrating regulatory T cells and its possibility as a therapeutic target in renal cell carcinoma

2019

Atsunari Kawashima
Mitsunobu Matsumoto
Yujiro Kidani
Takahiro Yoshida
Makoto Matsushita
Yoko Koh
Kosuke Nakano
Yujiro Hayashi
Yu Ishizuya
Cong Wang
Taigo Kato
Takeshi Ujike
Kazutoshi Fujita
M. Uemura
Shimon Sakaguchi
M. Nagira
N. Ohkura
Hisashi Wada
Norio Nonomura

INTRODUCTION AND OBJECTIVE:Regulatory T cells (Treg) play an important role in the construction of immune status within the tumor microenvironment. On the other hand, in order to maximize the thera...

Keywords:

Renal cell carcinoma
Cancer research
CCR8
Medicine
Urology
tumor tissue

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