Transurethral enucleation of the prostate for treatment of benign prostatic hyperplasia in patients less than 50 years old

Objiective To evaluate the therapeutic effect of transurethral enucleation of the prostate for treatment of benign prostatic hyperplasia in patients below 50 years of age. Methods Twelve patients with benign prostatic hyperplasia patients (mean age 48.2 years,range 46-49 years) underwent transurethral enucleation of the prostate. The middle lobe and two lateral lobes were enucleated with the preprostatic sphincter and anterior fibromuscular stroma prereserved during the operation. The patients were followed up to evaluate the lower urinary tract symptoms and sexual activity after the surgery. Results The 12 patients were followed up for 3 to 6 months. The symptoms of lower urinary tract obstruction were improved obviously after the surgery,and the International Prostate Symptom Score (IPSS) decreased from 24±5.1 to 8.8±1.4 and peak urine flow rate (Qmax) increased from 8.1±4.2 ml/s to 20.1±4.2 ml/s at 3 months postoperatively. All the 12 cases had residual urine (12-44 ml) preoperatively,but after the surgery,only 4 still had residual urine of less than 30 ml. All the patients had normal erection function postoperatively,and 10 had normal ejaculation; the other 2 patients recovered normal ejaculation 3 and 5 months after the operation,respectively. Conclusion Transurethral enucleation can alleviate the low urinary tract obstruction symptom and improve the sexual function by avoiding preprostatic sphincter injury in relatively young patients with benign prostatic hyperplasia.