Preparation and performance of biodegradable crosslinked PVP materials

A series of biodegradable crosslinking agents, di-acrylate of polyethylene glycol and polylactides (PLA-b-PEG-b-PLA)tri-block copolymer, were synthesized. And then the novel biodegradable crosslinked PVP membrane materials were prepared by radical polymerization with biodegradable crosslinking agents and N-vinyl pyrrolidone (NVP) using azoisobutyronitrile (AIBN) as initiator. The performance of PVP membrane materials was investigated. The results showed that the intrinsic viscosity of crosslinking agents would be regulated by changing the ratio of lactide to PEG. The water absorption would decrease, while the contact angle and the tensile module would increase with increasing the content of crosslinking agents, but extension at break would increase at first and decrease at last. The water absorption and the contact angle would increase with increasing the molecule weights of crosslinking agents. In the degradation process, the mass-loss rate of the materials showed specific original kinetic in the initial duration, but it increased dramatically at last.