tissue factor, its biological function and role in the etiology of prostate cancer

Tissue factor (TF) is a substance of great biological relevance. TF activates the extrinsic coagulation cascade and takes part in the mechanisms of inflammation and atheromatosis. TF, through its influence on neoangiogenesis, plays a great, but not exactly recognized, role in the origin and spread of neoplasms, including prostate cancer.