Chemical Composition and Biological Activity of the Essential Oil of Perovskia atriplicifolia. from Pakistan
2007
AbstractThe current study describes the phytochemical profile, antimicrobial, mutagenic, and antimutagenic activity of Perovskia atriplicifolia. Benth. essential oil, collected in Pakistan. The sample of essential oil was obtained from aerial parts of the plant by hydrodistillation and analyzed by gas chromatography–mass spectrometry. From the 18 compounds identified, the major compounds were camphor (28.91%), limonene (16.72%), α.-globulol (10.21%), trans.-caryophyllene (9.30%), and α.-humulene (9.25%). Antimicrobial activity of the oil was evaluated using agar diffusion method and agar dilution method. The antimicrobial test results showed that the oil had a significant potential antimicrobial activity against 10 bacteria and 5 fungal strains. Furthermore, the mutagenic and antimutagenic activity of the oil was investigated through the Salmonella./microsome test system, with and without S9 metabolic fraction in Salmonella typhimurium. TA98 and TA100. None of the tested concentrations of oil was found mu...
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