Synovial Sarcoma Metastasized to the Brain

Synovial sarcoma to the brain can be distinguished into three main groups. First, there are the very rare patients with the tumor originating intracranially; second, patients with a primary tumor originating in the head and neck region and infiltrating the brain through the skull base; and third, patients with hematogenous metastases to the brain. The first two groups should be treated as patients with a primary synovial sarcoma, intending to offer radical treatment. Surgery with negative margins if possible should be offered and radiotherapy and chemotherapy should be added as necessary. Treatment of patients of the third group is mainly palliative at the moment.