Stereocontrolled intramolecular cyclization of anti-β-aminonitriles. Convenient access to trans-azetidin-2-imines

Tz. Gospodova,J. R. Rashkova,Lilia Viteva

Stereocontrolled intramolecular cyclization of anti-β-aminonitriles. Convenient access to trans-azetidin-2-imines

2008

Tz. Gospodova
J. R. Rashkova
Lilia Viteva

We have developed a convenient approach to synthesis of trans-azetidin-2-imines, consisting in stereocontrolled cyclization of anti-β-amino nitriles in boiling ethanol in the presence of hydrochloric acid.

Keywords:

Hydrochloric acid
Radical cyclization
Organic chemistry
Ethanol
Chemistry
Intramolecular force
Photochemistry
Boiling
intramolecular cyclization

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