Preoperative neoadjuvant therapy for locally advanced rectal cancer

Preoperative radiotherapy combined with chemotherapy and (or) targeted therapy not only reduces the local recurrence of locally advanced rectal cancer and increases the rate of anal preservation and pathologic complete response,but also improves patient compliance.Preoperative neoadjuvant therapy will gradually become the standard treatment for locally advanced rectal cancer. Key words: Rectal neoplasms ;  Radiotherapy ;  Chemotherapy