Ezetimibe tablet and preparation method thereof

2015 
The invention provides an ezetimibe tablet and a preparation method thereof. The ezetimibe tablet is prepared from the following components in parts by weight: 10 parts of ezetimibe, 10 parts of a disintegrating agent, 2 parts of a solubilizing agent, 55 to 70 parts of a filling agent, 5 to 15 parts of microcrystalline cellulose, 5 parts of an adhesive and 0.5 parts of a lubricant. According to the ezetimibe tablet disclosed by the invention, the fluctuation of the dissolution of the ezetimibe tablet can be effectively reduced, the dissolution difference is reduced, the safety of the ezetimibe tablet in a medicine using process is improved, and the fluctuation of in-vivo absorption of the ezetimibe tablet is reduced; meanwhile, according to the preparation method of the ezetimibe tablet, a production process is simplified, and the method can adapt to large-scale industrial production.
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