Effect of β-blockers on bone mass and biomechanical parameters of the femoral neck in males with acute myocardial infarction

Abstract Objectives Evaluate the effect of cardioselective β-blockers on bone mass and biomechanical properties of the femoral neck in males with acute myocardial infarction. Methods Forty males with acute myocardial infarction were studied during one year. Seventy-five percent of the patients (30 patients) were treated with cardioselective β-blockers and 10 were not similarly treated. A hip densitometry was performed upon release and one year later. The BMD was measured in the femoral neck and in biomechanical elements obtained by DXA. Results Both groups had similar clinical conditions at the beginning of the study and after a one-year follow-up. No differences in the BMD (0.934 ± 0.12 vs. 0.921 ± 0.14) were observed in the group without β-blockers or in the group with β-blockers (0.980 ± 0.12 vs. 0.977 ± 0.12). No differences were observed in the measured structural parameters. Conclusion The cardioselective β-blockers do not modify bone mass or the structural bone parameters in males with acute myocardial infarction.