HBV genotype in 25 cases of patients with the hepatitis B virus.

Twenty-five HBV-DNA positive samples were randomly selected and used in hepatitis B virus(HBV) genotyping,and then the relationship between HBV serum biomarkers and ALT was studied.The results indicated that five samples were genotype B(20.00%),sixteen were genotype C(64.00%),and four samples were neither genotype B nor C(16.00%).With genotype B,HBeAg was positive in 40.00% of samples,and with genotype C HBeAg was positive in 93.75% of samples.With genotypes B and C,ALT was positive in 20.00% and 37.50% of cases,respectively.These results indicated that patients infected with HBV were mainly genotype C(93.75%),and more individuals infected with genotype C were positive for HBeAg than those infected with genotype B.HBV genotype C may be associated with HBV replication.