Особенности кардиоренального континуума у пациентов с метаболическим синдромом

THE AIM: to study of the cardiorenal relationships in patients with metabolic syndrome (MS). PATIENTS AND METHODS. 100 examined patients were divided into 4 groups: group 1 of 35 patients with primary pathology of the cardiovascular system (control), group 2 - 17 patients with cardiorenal syndrome 2 type (CRS2), group 3 - 19 patients with MS, group 4 - 29 patients with combined MS and KRS2. RESULTS. Patients of the 4th group revealed the highest disease duration, comorbidity, dyslipidemia and renal dysfunction. Also, only in patients of this group the need to perform coronary stenting was increased 3.6 times. Glomerular filtration rate (GFR) negatively correlated with the index of left ventricle myocardial mass and the end-diastolic volume of the left ventricle, despite the fact that the last two indicators did not exceed normal values. In patients of all groups noted the lack of character of cardio/renal protection therapy. CONCLUSION. The development of metabolic disorders and decrease in GFR caused by inadequate treatment of the underlying disease of the cardiovascular system and the absence of lifestyle changes. It is necessary to perform GFR monitoring in all patients with a primary pathology of the cardiovascular system, since the age of 40 years. Increase age declining more than 1 ml/min/1,73m 2 per year requires correction of the treatment.