Silencing of EPCAM suppresses hepatic fibrosis and hepatic stellate cell proliferation in mice with alcoholic hepatitis via the PI3K/Akt/mTOR signaling pathway

Zhi Zhang,Huiqing Wen,Jun Weng,Lei Feng,Hongya Liu,Xiaojun Hu,Fanhong Zeng

Silencing of EPCAM suppresses hepatic fibrosis and hepatic stellate cell proliferation in mice with alcoholic hepatitis via the PI3K/Akt/mTOR signaling pathway

2019

Zhi Zhang
Huiqing Wen
Jun Weng
Lei Feng
Hongya Liu
Xiaojun Hu
Fanhong Zeng

ABSTRACTAlcoholic hepatitis (AH) is a severe condition developed in patients with underlying alcoholic liver disease. Epithelial cell adhesion molecule (EPCAM) plays a role in hepatitis. Therefore,...

Keywords:

Cell biology
PI3K/AKT/mTOR pathway
Hepatic stellate cell
Hepatitis
Alcoholic liver disease
Protein kinase B
Biology
Hepatic stellate cell proliferation
Epithelial cell adhesion molecule
Alcoholic hepatitis
hepatic fibrosis
Cancer research
Molecular biology

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