Naproxen eugenol ester medicinal compound and preparation method of naproxen eugenol ester medicinal compound

2012 
The invention discloses a naproxen eugenol ester medicinal compound and belongs to propionic acid, 2-(6-methoxy group) naphthalin and 2-methoxyl group-4-(2- allyl) phenyl ester. According to the compound, naproxen is used as raw materials, the acylation is carried out, the naproxen with eugenol are subjected to esterification reaction in dissolvent, and the compound is prepared through recrystallization and purification. Through being used as efficient medicinal ingredients, the compound can be prepared into solid preparations, liquid preparations, injections, ophthalmic preparations, ointments, suppositories, film agents, aerosol or external preparations for clinical diseases of anti-inflammatory, antipyretic and analgesics and the like, particularly for diseases caused by infection.
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