Pegcetacoplan versus Eculizumab in Paroxysmal Nocturnal Hemoglobinuria

Peter Hillmen,Jeff Szer,Ilene C. Weitz,Alexander Röth,Britta Höchsmann,Jens Panse,Kensuke Usuki,Morag Griffin,Jean-Jacques Kiladjian,Carlos M. de Castro,Hisakazu Nishimori,Lisa Tan,Mohamed Hamdani,Pascal Deschatelets,Cedric Francois,Federico Grossi,Temitayo Ajayi,Antonio M. Risitano,Regis Peffault de la Tour

Pegcetacoplan versus Eculizumab in Paroxysmal Nocturnal Hemoglobinuria

2021

Peter Hillmen
Jeff Szer
Ilene C. Weitz
Alexander Röth
Britta Höchsmann
Jens Panse
Kensuke Usuki
Morag Griffin
Jean-Jacques Kiladjian
Carlos M. de Castro
Hisakazu Nishimori
Lisa Tan
Mohamed Hamdani
Pascal Deschatelets
Cedric Francois
Federico Grossi
Temitayo Ajayi
Antonio M. Risitano
Regis Peffault de la Tour

Abstract Background Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, acquired disease characterized by chronic complement-mediated hemolysis. C5 inhibition controls intravascular hemolysis in u...

Keywords:

Eculizumab
Internal medicine
Clinical trial
Medicine
Pharmacotherapy
Randomized controlled trial
Hemoglobinuria
Monoclonal
Paroxysmal nocturnal hemoglobinuria
Hemolysis
Gastroenterology

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