Decoquinate solid dispersoid and preparation method thereof

The invention relates to a decoquinate solid dispersoid and a preparation method thereof. The decoquinate solid dispersoid consists of decoquinate and a macromolecular carrier which are added with proper amount of surfactant. The mass ratio of the decoquinate to the macromolecular carrier is 1:0.5-1:12, preferably 1:0.8-1:8, and optimally 1:1-1:5. The preparation method comprises the following steps: dissolving the macromolecular carrier into a corresponding solvent first, and then suspending the decoquinate in the obtained solution; adding the surfactant to the solution; homogenizing the mixture through a high-pressure homogenizer or a colloid mill; and smashing the mixture into fine powder after spray drying or reduced-pressure drying to obtain the decoquinate solid dispersoid. The decoquinate solid dispersoid solves the difficulty that the decoquinate has poor hydrophilia and is not easy to disperse in water, can be watered for use clinically and has more convenient application. The preparation method has the advantages of simple process, short production cycle, and low energy consumption without residual solvent, and is applicable to industrial production.