Oxidation of polyamines in human seminal plasma: a possible role in immunological infertility.

Sixty-two specimens of seminal plasma obtained from normozoospermic, oligozoospermic, azoospermic, and immunologically infertile males were investigated. The levels of spermine, basal aldehyde, and aldehyde oxidation products were measured, as was the immunosuppressive activity of seminal plasma. No immunosuppressive activity was found in the immunologically infertile group; all other groups showed immunosuppressive activity. The immunologically infertile males showed low aldehyde oxidation products.