Osteopontin signaling upregulates cyclooxygenase-2 expression in tumor-associated macrophages leading to enhanced angiogenesis and melanoma growth via α9β1 integrin.

Smita Kale,Remya Raja,Dhanashri Thorat,Gowrishankar Soundararajan,T V Patil,Gopal C. Kundu

Osteopontin signaling upregulates cyclooxygenase-2 expression in tumor-associated macrophages leading to enhanced angiogenesis and melanoma growth via α9β1 integrin.

2014

Smita Kale
Remya Raja
Dhanashri Thorat
Gowrishankar Soundararajan
T V Patil
Gopal C. Kundu

Osteopontin signaling upregulates cyclooxygenase-2 expression in tumor-associated macrophages leading to enhanced angiogenesis and melanoma growth via α9β1 integrin

Keywords:

Cancer research
Melanoma
Osteopontin
Angiogenesis
Integrin
Cyclooxygenase
Biology
Cancer cell
Autocrine signalling
Tumor microenvironment
MAPK/ERK pathway
Downregulation and upregulation

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