Determining issues of importance for patients with lung cancer: Results of a web-based study in 660 patients with lung cancer to enhance the content validity of quality of life (QL) instruments

20518 Background: Identifying key issues for patients with cancer is central to assessing QL and patient reported outcomes (PROs), which aids in evaluating effectiveness of treatment programs for those with the disease. The first aim of this study was to enhance the content validity for the PRO instrument, the LCSS, by enlarging the patient panel (originally 121) with an additional 660 patients. These data can also be useful for any QL or symptom scale as well as helping to ascertain that programs address the needs expressed by patients. Methods: We used the established patient base of the web-based NexCura patient information resource to survey registered patients with lung cancer. Demographic stratifications included: stage of disease (metastatic 27%, locally advanced 37%, NED 36%); gender (55% women); KPS (≥80 = 46%, 70 = 28%, 60 = 16%); median age 62; NSCLC = 82%, SCLC = 18%; current treatment. 660 patients completed the anonymous web-conducted survey. Patients were asked to rank 20 issues on a 5-poin...