The anti-oxidant prophylaxis for cellular injury in ovarian surface epithelium resulting from CO2 pneumoperitoneum in laparoscopic rat model

Objective Selective cytoprotective functions of vitamin E, N-acetyl-l-cysteine, and amifostine have been used as a preventer of ischemia injury by expelling the free oxygen radicals leading to stabilization of the cellular membranes. The purpose of this experimental study was to investigate the oxidative stress related to cellular injury in ovarian surface epithelium and the effect of prophylaxis with an anti-oxidant using laparoscopic rat model.