Abstract MP55: Endothelial Sirtuin-1 Deficiency Promotes the Rupture of Intracranial Aneurysm

James Purcell,Hiroki Sato,Taichi Ikedo,Francesca Seta,Jinglu Ai,Michael T. Lawton,Tomoki Hashimoto

Abstract MP55: Endothelial Sirtuin-1 Deficiency Promotes the Rupture of Intracranial Aneurysm

2021

James Purcell
Hiroki Sato
Taichi Ikedo
Francesca Seta
Jinglu Ai
Michael T. Lawton
Tomoki Hashimoto

Background: Sirtuin-1 is highly expressed in vascular tissues and plays an important role in numerous metabolic and inflammatory processes. Age-related reduction in Sirtuin-1 expression has been li...

Keywords:

Vascular tissue
Cancer research
Medicine
Sirtuin 1
Aneurysm
Endothelium

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