[Changes in the activities of oxidoreductases, content of malondialdehyde and medium weight molecules in the blood of patients with craniocerebral injuries of different severity].

: Biochemical changes are determined by the severity of craniocerebral injury. Twenty-four hours after the injury the activity of succinate dehydrogenase in lymphocytes increases significantly in patients with brain concussion and contusion of medium severity. Glutamate dehydrogenase activity increases in patients with repeated brain concussion. The content of malonic dialdehyde is increased in patients with repeated brain concussion and decreased in severe brain contusion. The level of medium-weight molecules is increased in all patients with craniocerebral injuries. The activities of these enzymes are virtually unchanged in the patients with lethal outcomes.