Specific IgA response in small intestine during experimental toxoplasmosis

144 Swiss Webster outbred mice were orally inoculated by 30 cysts of Toxoplasma gondii (PRUGNIAUD strain). Intestinal washings and blood samples were obtained at different times post-infection (P.I.) from day 1 P.I. to 67 P.I. At day 67 P.I., 32 animals were reinfested in the same way and, then sacrificated at several days post-reinfection (P.R.). Serum samples and small intestine washings,first filtered, were analysed for IgA, IgG and IgM detection by a classic ELISA method.