HLA-identical umbilical cord blood transplantation from a sibling donor in juvenile myelomonocytic leukemia

As recently described by Flotho et al . juvenile myelomonocytic leukemia (JMML) is a rare type of childhood leukemia not only characterized by young age, hepatosplenomegaly, thrombocytopenia and monocytosis, but also by molecular aberrations in the RAS-RAF-MEK-ERK signaling pathway and GM-CSF-