Case Report Pleomorphic carcinoma of breast: a case report and review of literature

* Equal contributors. Received June 9, 2014; Accepted July 16, 2014; Epub July 15, 2014; Published August 1, 2014 Abstract: Pleomorphic carcinoma of the breast is a rare variant of invasive breast carcinoma. Here, we report a case in a 45-year-old woman presenting a lesion composed microscopically of predominantly pleomorphic giant cells, squamous metaplastic component and focal conventional ductal carcinoma. Immunohistochemical assay showed different immunologic manifestation in respective malignant components. Despite positive lymph node metastasis, the patient has been well without evidence of recurrence or metastasis two years after operation. The implication of this report is to provide insights into further understanding of this rare tumor with review of the literature.