MP17-08 HLA-E EXPRESSION PREDICTS PROGRESSION, THERAPEUTIC RESPONSE AND OVERALL SURVIVAL IN PATIENTS WITH BLADDER CANCER

Jorge Daza,Dan Fu Ruan,Bérengère Salomé,Andrew Charap,Peter Wiklund,Matthew D. Galsky,Petros Grivas,Reza Mehrazin,John P. Sfakianos,Amir Horowitz

MP17-08 HLA-E EXPRESSION PREDICTS PROGRESSION, THERAPEUTIC RESPONSE AND OVERALL SURVIVAL IN PATIENTS WITH BLADDER CANCER

2020

Jorge Daza
Dan Fu Ruan
Bérengère Salomé
Andrew Charap
Peter Wiklund
Matthew D. Galsky
Petros Grivas
Reza Mehrazin
John P. Sfakianos
Amir Horowitz

INTRODUCTION AND OBJECTIVE:Binding of HLA-E to CD94/NKG2A expressed on NK and CD8 T cells is strongly associated with impaired anti-tumor immunity. We aimed to demonstrate that HLA-E expression is ...

Keywords:

overall survival
Oncology
in patient
Internal medicine
Urology
HLA-E
Bladder cancer
Medicine
Cytotoxic T cell
Immunity
Pathology

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