Multi-factors analysis on prognostic of in-hospital patients with gastrointestinal bleeding

Objective To investigate the prognostic factors of in-hospital patients with gastrointestinal bleeding(GIB).Methods Clinical data of patients with GIB admitted from January 1 to December 31,2006 in Daqing oil field general hospital were analyzed retrospectively.Results The mortality of in-hospital patients with GIB was significantly higher than the overall mortality of in-hospital patients(15.8% vs 1.8%).The mortality was significantly higher in elderly and middle-aged patients than that in young patients(19.9%,15.0%and 5.8%,respectively).The mortality was significantly higher in patients with symptom of only haematemesis and with symptoms of haematemesis concomitant hematochezia than those with only hematochezia(19.0%,22.9% and 8.2%,respectively).There was a significantly higher mortality in patients with massive haematemesis500 mL than those ≤500 mL(34.6% vs 15.5%).The mortality of patients whose first haemoglobin levels ≤90.0 g/L after bleeding was significantly higher than those 90.0 g/L(20.9% vs 12.4%).The mortality of patients with malignant tumors was highest(57.9%),the second was patients with esophagogastric varices(36.4%) and the mortality of patients with peptic ulcer was 1.5%.A non-conditional multivariate logistic regression analysis of all aforementioned factors revealed that age, clinical presenting manifestations of bleeding,the high-volume of haematemesis(500 mL) and haemoglobin levels were of prognostic importance for the mortality of patients with GIB.Primary diseases including malignant tumor,esophagogastric varices and peptic ulcer also were independent risk factors for in-hospital mortality.Conclusion GIB remains an important cause of in-hospital mortality.Age,the high-volume of haematemesis(500 mL),haemoglobin levels and primary diseases(malignant tumor,esophagogastric varices,et al) are independent prognostic factors of mortality in patients with GIB.