EFFECTS OF A DIRECT RENNIN INHIBITOR OR A DIURETIC ADDED ON AN ANGIOTENSIN II RECEPTOR BLOCKER ON CENTRAL AORTIC PRESSURE IN HYPERTENSIVE PATIENTS (ALEA STUDY)

To achieve the target blood pressure recommended by the latest guidelines, multiple antihypertensive drugs are needed in most patients. Furthermore, recent studies showed that central aortic pressure is closely associated with target organ damages. We compared the effects of a direct rennin