Placental growth factor negatively regulates retinal endothelial cell barrier function through suppression of glucose-6-phosphate dehydrogenase and antioxidant defense systems

Hu Huang,Anton Lennikov,Madhu Sudhana Saddala,David Gozal,Dennis J. Grab,Abdelnaby Khalyfa,Lijuan Fan

Placental growth factor negatively regulates retinal endothelial cell barrier function through suppression of glucose-6-phosphate dehydrogenase and antioxidant defense systems

2019

Hu Huang
Anton Lennikov
Madhu Sudhana Saddala
David Gozal
Dennis J. Grab
Abdelnaby Khalyfa
Lijuan Fan

We report that placental growth factor (PlGF) negatively affects the endothelial cell (EC) barrier function through a novel regulatory mechanism. The PlGF mAb promotes (but recombinant protein disr...

Keywords:

Endothelial stem cell
Recombinant DNA
Retina
Glucose-6-phosphate dehydrogenase
Retinal
Internal medicine
Biology
Endocrinology
Barrier function
Diabetic retinopathy
Placental growth factor

Correction
Source
Cite
Save
Machine Reading By IdeaReader

References

Citations