SYNTHESIS OF MAGNETITE NANOPARTICLES ENCAPSULATED WITH POLYANILINE AND THEIR INDUCTIVE HEATING PROPERTY IN ALTERNATING CURRENT MAGNETIC FIELD

The Fe_3O_4/polyaniline composite nanoparticles with diameters of 30～50nm were prepared.The Fe_3O_4 nanoparticles with diameters of 10～30nm were encapsulated with polyaniline(PANI) by in-situ polymerization.The inductive heating property of Fe_3O_4 nanoparticles and Fe_3O_4/polyaniline composite nanoparticles in an alternating current magnetic field was investigated.The potential of the two kinds of nanoparticles was evaluated for the(localized) hyperthermia treatment of cancers.The saturation magnetization M_s and coercivity H_c of Fe_3O_4 nanoparticles(are 50.05emu/g) and 137 Oe respectively,the Fe_3O_4/polyaniline composite nanoparticles,26.34emu/g and 0 Oe.Exposed in the alternating current magnetic field for 30 min,the temperatures of physiological salt water suspension containing Fe_3O_4 nanoparticles or Fe_3O_4/polyaniline composite nanoparticles are 63.6℃ and 52.4℃ respectively.These two kinds of nanoparticles would be useful as good thermoseeds for the localized hyperthermia treatment of cancers.