Separation by Microfiltration of Pseudomonas Aeruginosa Cells from the Culture Broth

The paper presents the experimental research to redesign the separation stage of a bacterial immune modulator of pharmaceutical use, to be integrated into the GMP (Good Manufacturing Practice) small scale bio product manufacture aseptic, closed flow. It will be studed the separation characteristics for each technological operation, the membrane regeneration capacity and evaluated the period of working time.