MAJÖR TÜKÜRÜK BEZİ KİTLELERİNDE İNCE İĞNE ASPİRASYON BİYOPSİSİNİN TANISAL DEĞERİ

OZ: Amac: Major tukuruk bezi kitlelerinin tanisinda ince igne aspirasyon biyopsisinin (iiAB) degerinin tartisilmasi. Gerec ve Yontem: Haziran 2005-Aralik 2008 tarihleri arasinda klinigimizde major tukruk bezi kitlesi nedeniyle opere edilen ve tetkik sonuclarina ulasilabilen 54 hastanin preoperatif iiAB sonuclari ile operasyon materyalinin histopatolojik degerlendirmesi ile elde edilen sonuclar karsilastirildi. iiAB’nin duyarlilik, ozgulluk, tani dogrulugu parotis, submandibuler bez ve tum hastalar icin arastirildi. Bulgular: iiAB’nin 24’u (%44,4) parotis, 30’u (%55,5) submandibular kitleden yapilmistir. Bu materyallerden 49’u (%90,7) benign, 3’u (%5,55) malign, 2’si (%3,7) yetersiz materyal tanisi almistir. Histopatolojik degerlendirme sonucu malign oldugu tespit edilen olgularda iiAB ile iki olguda yalanci negatif sonuc elde edilirken, 1 olguda gercek pozitif sonuc elde edilmistir. Tum olgularda duyarlilik, ozgulluk ve dogruluk oranlari sirasiyla %33,3 %100, %92,6 olarak elde edilmistir. Sonuc: Major tukruk bezi kitelerinde iiAB sonucunun benign olmasi malignite ihtimalini ortadan kaldirmaz. Bu acidan hastanin degerlendirilmesinde klinik bulgular, ultrasonografi, bilgisayarli tomografi gibi diger tani metodlarinin bulgulari ve iiAB sonuclari birlikte kullanilmalidir. Anahtar Kelimeler: Ince Igne Aspirasyon Biyopsisi, Parotis Bezi, Submandibuler Bez DIAGNOSTIC VALUE OF FINE-NEEDLE ASPIRATION BIOPSY IN THE MAJOR SALIVARY GLAND MASSES ABSTRACT: Purpose: To discuss the value of fine needle aspiration biopsy in the diagnosis of major salivary gland masses. Material and Method: Among the patients operated between 2005 and 2008, FNAB results of 54 patients were available and were compared to histopathologic diagnosis. Sensitivity, specificity and accuracy rate of FNAB were investigated for parotid, submandibular salivary glands and for the whole patient population. Results: FNAB was performed on 24 (44,4%) parotid and 30 (55,5%) submandibular salivary gland masses. Forty-nine of these masses (90,7%) were classified as benign, three (5,55%) were malignant, and two (3,7%) were reported as insufficient material. Among the cases determined to be malignant by histopathologic evaluation, there were two false negatives and one true positive result by FNAB. Sensitivity, specificity and correct diagnosis rates were 33,3%, 100%, 96,1%, respectively. Conclusion: A benign FNAB result does not necessarily exclude a malignancy in major salivary gland masses. So, the patients should be evaluated taking into account the clinical findings, FNAB results and other diagnostic methods like utrasonography, computed tomography. Key Words: Fine Needle Aspiration Biopsy, Parotid Gland, Submandibular Gland