INTRAVASCULAR LARGE B-CELL LYMPHOMA PRESENTING AS THYROID, ADRENAL AND MESENTERIC NODULES

ABSTRACT Objective: Identification of multiple endocrine abnormalities can result from endocrine or nonendocrine malignancies, genetic syndromes, or systemic diseases. Here, we evaluate an unusual presentation of several endocrine pathologies. Methods: We present a female with multiple endocrine abnormalities who was ultimately diagnosed with intravascular large B-cell lymphoma (IVLBCL). We also review the literature on IVLBCL, including presentation, management, treatment, and outcomes. Results: A 52-year-old woman with multinodular goiter presented with an enlarging thyroid nodule. Fine needle aspiration revealed a high-grade neoplasm of unclear etiology. Due to a history of nephrolithiasis, the patient was also evaluated for and found to have probable primary hyperparathyroidism. Magnetic resonance imaging performed for lumbar pain identified an incidental indeterminate 2.7-cm nonfunctioning adrenal nodule. [18F]-fluorodeoxyglucose (FDG) positron emission tomography–computed tomography (PET-CT) demonst...