Technetium-99m-HMPAO-Labeled Leukocytes and Technetium-99m-Labeled Human Polyclonal Immunoglobulin G in Diagnosis of Focal Purulent Disease

leuko cytesands@Trro4abaled po@onalhumanimmunoglobulin G (Technescan HIG)inthediagnosia offocalpurulent dinease, 31 comparative ScintigraphieS weredonein30patients withknown orstrongly suspected focalinfedion. Focal purulent disease was thefinaldiagnosis in 19patients. Technetium-99m-Iabeled leu kocytes showed16true-positive, nofalse-positive, 11true-nag ativeand3 false-negative findings.Thecorresponding figures for @“Tc-Itheled HIGwereI 1, 2, 9 and8. Thesensitivity and spedifolty of ima@ng w@ilabeled leukocytes were84%and 100%, respectively, and with labeled HIG, 58% and 82%, re spectively. Theoverallaccuracy oftheleukocyte scanwassig niflcantlybetterthanthatofthe HIGscan(90%versus67%,p < 0.001). Thus, it focal infectionis suspected, scintigraphywith 9@'1@c-Iabeled leukocytes is the preferable method.No cases e@thibfted a betterima@ng resuftwith @Fo-HlG sdntigraphy thanwith°°“Tc-labeled leukocytes.