A randomized, double-blinded, placebo-controlled phase II trial of gemcitabine (gem) plus nab-paclitaxel (nab-P) plus apatorsen (A) or placebo (Pl) in patients (pts) with metastatic pancreatic cancer (mPC): The RAINIER trial.

Andrew H. Ko,P. B. Murphy,J. D. Peyton,Dianna Shipley,Ahmed Al-Hazzouri,Francisco Antonio Rodriguez,Mark S. Womack,Henry Q. Xiong,David Waterhouse,Margaret A. Tempero,Shuangli Guo,Cassie M. Lane,Christopher Earwood,Laura M. DeBusk,Johanna C. Bendell

A randomized, double-blinded, placebo-controlled phase II trial of gemcitabine (gem) plus nab-paclitaxel (nab-P) plus apatorsen (A) or placebo (Pl) in patients (pts) with metastatic pancreatic cancer (mPC): The RAINIER trial.

2016

Andrew H. Ko
P. B. Murphy
J. D. Peyton
Dianna Shipley
Ahmed Al-Hazzouri
Francisco Antonio Rodriguez
Mark S. Womack
Henry Q. Xiong
David Waterhouse
Margaret A. Tempero
Shuangli Guo
Cassie M. Lane
Christopher Earwood
Laura M. DeBusk
Johanna C. Bendell

4119Background: Over expression of heat shock protein 27 (Hsp27) in PC promotes tumor growth and metastasis, and is associated with poor prognosis. A is an antisense oligonucleotide that binds to H...

Keywords:

Placebo
Nab-paclitaxel
Metastatic pancreatic cancer
Pathology
Oncology
Gemcitabine
Internal medicine
Medicine
Metastasis
Heat shock protein
in patient
double blinded
Hsp27

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